Li Su, Ph.D., Associate Professor, Master Supervisor

Tel.: +86 13519441087

E-mail: sul@lzu.edu.cn

Education

2008-2011: Ph.D. in Zoology, Lanzhou University

2001-2004: M.M. in Toxicology, Lanzhou University

1996-2001: B.M. in Public Health, Lanzhou University

Employment

2016-2017: Visiting Scholar, Health Science Center, University of Louisville, Kentucky, USA

2012-        : Associated Professor, School of Public Health, Lanzhou University, Lanzhou, China

2007-2012: Lecturer, School of Public Health, Lanzhou University, Lanzhou, China

2004-2007: Teaching Assistant, School of Public Health, Lanzhou University, Lanzhou, China

Honors & Awards

1. Research project “Study of the Effect of Vitamin A and Zinc Intake on Rats and Special Population” was awarded the Third Class of Scientific and Technological Progress Award in Gansu Province in 2010, Gansu, China

2. Research project “Investigation of Zinc, Vitamin A, and Vitamin C Deficiency in 3 to 6 years old children of Yugu, Dongxiang and Bao’an nationalities and their complex nutritional intervention” was awarded the Third Class of Scientific and Technological Progress Award in Gansu Province in 2009, Gansu, China

Teaching Courses

Toxicology, Advances in Toxicology, Hygiene, Preventive Medicine

Professional Service

Director of Nutrition Society in Gansu Province, China

Reviewer, the Journal of Toxicology Letters

Reviewer, the Journal of Toxicology (Chinese)

Research Interests

To understand the cellular and molecular mechanisms of reproductive toxicity induced by nickel through mediating energy metabolism, the mechanisms of mitochondrial DNA damage in spermatogonial cells of mice which relies on the decrease of mtDNA copy number and mtDNA deletions, and the regulatory mechanisms of ROS and MAPK in modulating testosterone secretion of Leydig cells following exposure to nickel.

Academic Projects

1. Project Director, The regulatory mechanisms of microRNA in modulating testosterone secretion of Leydig cells following exposure to nickel (No.lzujbky-2018-67), the Fundamental Research Funds for the Central Universities, 2018.1.1~2019.12.31

2. Project Director, The regulatory mechanisms of ROS and MAPK in modulating testosterone secretion of Leydig cells following exposure to nickel (No 81402703), the National Natural Science Foundation of China, 2015.1.1~2017.12.31

3. Project Director, The mechanisms of endoplasmic reticulum stress and mitochondrial apoptosis induced by nickel in Leydig cells of rats (Lzujbky-2015-89), the Fundamental Research Funds for the Central Universities, 2015.1.1~2016.6.30

4. Project Director, Acute toxicity studies of water purificated by household water purifier (No.2012620111000155), Cooperate Program with Enterprise, 2012.1.1~2014.12.31

5. Project Director, The mechanisms of mitochondrial DNA damage and repair in spermatogonial cells of mice (Lzujbky-2012-158), the Fundamental Research Funds for the Central Universities, 2012.1.1~2013.6.30

6. Project Director, The study on influence factors and group characteristics of consumers for weight-losing products in Gansu (No.2011620111000578), Cooperate Program with Enterprise, 2011.12.1~2012.12.31

7. Project Director, The Study on the disorder of energy metabolism induced by nickel in testes of rats (Lzujbky-2009-89), the Fundamental Research Funds for the Central Universities, 2010.1.1~2010.12.31

8. Project Director, The protective effects of procyanidin on reproductive damage induced by nickel sulfate of male rats (No. Lzujc200921), the Interdisciplinary Research Funds Program for Youth, 2010.1.1~2011.12.31

9. Participant, The Study on PBTK model and pulmonary toxic effects of nano NiO (Lzujbky-2015-186), the Fundamental Research Funds for the Central Universities, 2015.1.1~2016.6.30

10. Participant, Investigation of malnutrition and intervention of complex nutrition of 0 to 6 years old children in Ethnic Population of Yugu, Dongxiang and Bao’an (2001-001), danone institute foundation for nutrition research and education, 2002.1~2003.12

Representative Achievements

1. Aijie Han, Lingyue Zou, Xiaoqin Gan, Yu Li, Fangfang Liu, Xuhong Chang, Xiaotian Zhang, Minmin Tian, Sheng Li, Li Su*, Yingbiao Sun*. ROS generation and MAPK activation contribute to the NiSO4-induced testosterone synthesis disturbance in rat Leydigcells[J]. Toxicology Letters, 2018, 290(15), 36-45. Corresponding author.

2. Lingyue Zou, Li Su, Yifan Sun, Aijie Han, Xuhong Chang, An Zhu, Fangfang Liu, Jin Li, Yingbiao Sun*, Nickel sulfate induced apoptosis via activating ROS-dependent mitochondria and endoplasmic reticulum stress pathways in rat Leydig cells, Environmental Toxicology, 2017, 32(7), 1918-1926.

3. Li Su, Yuantao Deng, Rui Zhang, et al. The protective effects of procyanidin on reproductive damage induced by nickel sulfate of male rats[J]. Industrial Health and Occupational Diseases, 2015, 41(1):16-18. (Chinese)

4. Fang Guo, Yingbiao Sun, Li Su, et al. Losartan attenuates paraquat-induced pulmonary fibrosis in rats[J], Human and Experimental Toxicology, 2015, 34(5), 497-505.

5. Zhifei Liu, Yingbiao Sun, Li Su, et al. Effects of cisplatin on testicular enzymes and Sertoli cell function in rats[J], Fundamental Toxicological Sciences, 2015, 2(4):137-145.

6. Li Su, Xuhong Chang, Jin Li, et al. Effects of nickel sulfate on mouse spermatogonial cells in vitro[J]. Journal of Toxicology, 2013, 27(5): 55-57. (Chinese)

7. Qiaoyun Liu, Kai Liu, Li Su. Survey on KAP of breast health and cognition of breast carcinoma among female college students in Lanzhou[J]. Chinese Journal of School Health, 2013, 31(2): 237-238. Corresponding author. (Chinese)

8. Li Su, Chengyun Li, Rui Zhang, et al. Effects of nickel sulfate on energy metabolism of testicular cells in rats[J]. Journal of Toxicology, 2012, 26(1): 1-4. (Chinese)

9. Li Su, Yuantao Deng, Yingmei Zhang, et al. Protective effects of grape seed proancyanidin extracts against nickel sulfate-induced apoptosis and oxidative stress in rat testes[J]. Toxicology Mechanisms and Methods, 2011, 21(6): 487-494.

10. Li Su, Yuantao Deng, Rui Zhang, et al. Effects of nickel sulfate on testicular cells in rats[J]. Chinese Journal of Public Health, 2011, 37(12):1597-1598. (Chinese).